DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia.

Dicke AK, Pilatz A, Wyrwoll MJ, Punab M, Ruckert C, Nagirnaja L, Aston KI, Conrad DF, Di Persio S, Neuhaus N, Fietz D, Laan M, Stallmeyer B, Tüttelmann F
Communications Biology, 31. März 2023
Link zur Publikation.

Functional assessment of DMRT1 variants and their pathogenicity for isolated male infertility.

Emich J, Gaikwad AS, Stallmeyer B, Fietz D, Schuppe HC, Oud MS, Kliesch S, Gromoll J, Friedrich C, Tüttelmann F
Fertility and Sterility, 24. Dezember 2022
Link zur Publikation.

Genetic architecture of azoospermia-time to advance the standard of care.

Wyrwoll MJ, Köckerling N, Vockel M, Dicke AK, Rotte N, Pohl E, Emich J, Wöste M, Ruckert C, Wabschke R, Seggewiss J, Ledig S, Tewes AC, Stratis Y, Cremers JF, Wistuba J, Krallmann C, Kliesch S, Röpke A, Stallmeyer B, Friedrich C, Tüttelmann F
European Urology, 8. Juni 2022
Link zur Publikation.

Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest.

van der Bijl N, Röpke A, Biswas U, Wöste M, Jessberger R, Kliesch S, Friedrich C, Tüttelmann F
Human Reproduction, 4. November 2019
Link zur Publikation.

X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men.

Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfilippo J, Kurpisz M, Rajkovic A, Yatsenko S, Kliesch S, Schlatt St, Tüttelmann F
New England Journal of Medicine, 28. Mai 2015
Link zur Publikation.